Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility
نویسندگان
چکیده
منابع مشابه
Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility.
Protein evolution is crucial for organismal adaptation and fitness. This process takes place by shaping a given 3-dimensional fold for its particular biochemical function within the metabolic requirements and constraints of the environment. The complex interplay between sequence, structure, functionality, and stability that gives rise to a particular phenotype has limited the identification of ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0807989106